What is Adipex and how is it used?
Adipex is a prescription medicine used to treat the symptoms of obesity. Adipex may be used alone or with other medications. Adipex belongs to a class of drugs called CNS Stimulants, Anoxexiants; Stimulants; Sympathomimetic. It is not a first-choice medication for weight management because of side effects and the risk of abuse. It can be used short term if other similar medications haven't worked.
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What are the possible side effects of Adipex?
Adipex may cause serious side effects including:
feeling short of breath,
chest pain,
lightheadedness,
swelling in your ankles or feet,
pounding heartbeats,
fluttering in your chest,
tremors,
feeling restless,
trouble sleeping,
unusual changes in mood or behavior,
severe headache,
blurred vision,
pounding in your neck or ears,
anxiety, and
Nosebleed
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The most common side effects of Adipex include:
itching,
dizziness,
headache,
dry mouth,
unpleasant taste,
diarrhea,
constipation,
stomach pain, and
increased or decreased interest in sex
INDICATIONS
ADIPEX is indicated as a short-term (a few weeks) adjunct in a regimen of weight reduction based on exercise, behavioral modification and caloric restriction in the management of exogenous obesity for patients with an initial body mass index greater than or equal to 30 kg/m2, or greater than or equal to 27 kg/m2 in the presence of other risk factors (e.g., controlled hypertension, diabetes, hyperlipidemia).
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DOSAGE AND ADMINISTRATION
Exogenous Obesity
Dosage should be individualized to obtain an adequate response with the lowest effective dose. The usual adult dose is one capsule (37.5 mg) daily as prescribed by the physician, administered before breakfast or 1 to 2 hours after breakfast for appetite control. The usual adult dose is one tablet (37.5 mg) daily as prescribed by the physician, administered before breakfast or 1 to 2 hours after breakfast. The dosage may be adjusted to the patient’s needs. For some patients, half tablets (18.75 mg) daily may be adequate, while in some cases it may be desirable to give half tablets (18.75 mg) two times a day.
ADIPEX is not recommended for use in pediatric patients less than or equal to 16 years of age. Late evening medication should be avoided because of the possibility of resulting insomnia.
HOW SUPPLIED
Dosage Forms And Strengths
Capsules containing 37.5 mg phentermine hydrochloride (equivalent to 30 mg phentermine base). Tablets containing 37.5 mg phentermine hydrochloride (equivalent to 30 mg phentermine base).
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SIDE EFFECTS
The following adverse reactions are described, or described in greater detail, in other sections:
Primary pulmonary hypertension.
Valvular heart disease.
Effect on the ability to engage in potentially hazardous tasks .
Withdrawal effects following prolonged high dosage administration.
Cardiovascular
Primary pulmonary hypertension and/or regurgitant cardiac valvular disease, palpitation, tachycardia, elevation of blood pressure, ischemic events.
Central Nervous System
Overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, headache, psychosis.
Gastrointestinal
Dryness of the mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances.
Allergic
Urticaria.
Endocrine
Impotence, changes in libido.
DRUG INTERACTIONS
Monoamine Oxidase Inhibitors
Use of ADIPEX is contraindicated during or within 14 days following the administration of monoamine oxidase inhibitors because of the risk of hypertensive crisis.
Alcohol
Concomitant use of alcohol with ADIPEX may result in an adverse drug reaction.
Insulin And Oral Hypoglycemic Medications
Requirements may be altered.
Adrenergic Neuron Blocking Drugs
ADIPEX may decrease the hypotensive effect of adrenergic neuron blocking drugs.
Drug Abuse And Dependence
Controlled Substance
Phentermine is a Schedule IV controlled substance.
Abuse
Phentermine is related chemically and pharmacologically to amphetamines. Amphetamines and other stimulant drugs have been extensively abused and the possibility of abuse of phentermine should be kept in mind when evaluating the desirability of including a drug as part of a weight reduction program.
Dependence
Abuse of amphetamines and related drugs may be associated with intense psychological dependence and severe social dysfunction. There are reports of patients who have increased the dosage of these drugs to many times that recommended. Abrupt cessation following prolonged high dosage administration results in extreme fatigue and mental depression; changes are also noted on the sleep EEG.